Tiago J. P. Sobreira
Purdue University West Lafayette, State Street (United States)
Papers
4
Total Citations
141
H-Index
4
About
Tiago J. P. Sobreira is a pioneering researcher at the intersection of analytical chemistry, high-throughput experimentation, and synthetic chemistry, with a particular focus on accelerating organic reaction discovery and optimization. His most significant contributions center on the development and application of desorption electrospray ionization mass spectrometry (DESI-MS) as a powerful tool for ultra-rapid screening of chemical reactions, enabling the evaluation of thousands of reactions per day through intelligent integration of liquid handling robotics with advanced mass spectrometric analysis. Sobreira's landmark 2020 publications — collectively accumulating over 140 citations — demonstrate his ability to bridge hardware innovation, software development, and practical synthetic chemistry. His work spans reductive amination, nucleophilic aromatic substitution, and aldol reactions, including sustainable chemistry applications involving biorenewable platform molecules like triacetic acid lactone. Notably, his research consistently validates high-throughput findings through continuous flow chemistry, reinforcing real-world applicability. By compressing reaction screening timescales from weeks to hours, Sobreira's contributions are transforming how chemists approach reaction optimization, making him an influential figure for researchers working at the frontier of automated synthesis, green chemistry, and pharmaceutical process development.
Research Focus
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Top Papers
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