Ryan T. Hilger
Papers
1
Total Citations
52
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1
About
Ryan T. Hilger is a leading figure in the development of high-throughput screening methodologies for organic chemistry, with a particular focus on accelerating reaction discovery through microdroplet technology. His most cited work, a 2020 study on the hardware and software implementation of desorption electrospray ionization mass spectrometry (DESI-MS) for screening organic reactions, has garnered 52 citations. In this pivotal contribution, Hilger and his team engineered an automated system that exploits the accelerated reaction kinetics inherent in small-volume microdroplets. By integrating a fluid-handling robot to prepare reaction mixtures in an array format on a polytetrafluoroethylene plate, his work enables the rapid, parallel screening of numerous reaction conditions. This innovation dramatically reduces the time and material required for reaction optimization, bridging the gap between fundamental microdroplet chemistry and practical, high-throughput applications. Hilger's contributions are instrumental in advancing the field of automated chemical synthesis, providing researchers with powerful tools for accelerating the discovery of new reactions and catalysts.
Research Focus
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Top Papers
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