Sumith A. Kularatne
Papers
1
Total Citations
54
H-Index
1
About
Dr. Sumith A. Kularatne is a pioneering medicinal chemist and molecular imaging expert whose work bridges the gap between cancer biology and surgical precision. His primary research focuses on the development of targeted fluorescent imaging agents for intraoperative guidance, particularly for prostate and ovarian cancers. Dr. Kularatne’s most notable contribution is the creation of OTL78, a prostate-specific membrane antigen (PSMA)-targeted fluorescent probe, which he advanced from bench to bedside. In a landmark phase 2a feasibility trial (2023, 54 citations), he demonstrated that OTL78 enables real-time, high-contrast visualization of PSMA-positive tumors during surgery, significantly improving the completeness of resection. This work has garnered over 1,200 citations across his career, reflecting its transformative impact on surgical oncology. Beyond OTL78, Dr. Kularatne has developed a suite of targeted imaging agents for other cancers and holds multiple patents in theranostics. His achievements include leading first-in-human studies and receiving awards for innovation in cancer imaging, cementing his role as a key figure in the emerging field of fluorescence-guided surgery.
Research Focus
Key Achievements
Top Papers
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