Alexander L. Vahrmeijer

Leiden University Medical Center, Leiden University

Papers

12

Total Citations

443

H-Index

8

About

Alexander L. Vahrmeijer is a pioneer in image-guided surgery, with his research fundamentally advancing how surgeons visualize anatomy and pathology during operations. His core expertise lies in fluorescence-guided surgery, particularly using near-infrared imaging with indocyanine green (ICG) to improve outcomes in minimally invasive and robotic procedures. Vahrmeijer’s major contributions include demonstrating that ICG-fluorescence can assess bowel perfusion to prevent anastomotic leakage—a finding validated in the landmark, multicentre AVOID trial (84 citations). He has also shown that this technology enables real-time surgical margin assessment during laparoscopic and robot-assisted resections of colorectal liver metastases, a critical advance given that nearly a third of these procedures risk positive margins. His work extends to developing hybrid radioactive-fluorescent tracers that expand fluorescence guidance to deeper structures, and he led the first-in-patient study of OTL78 for prostate-specific membrane antigen-positive prostate cancer. With multiple papers exceeding 50 citations and leadership in nationwide implementation studies for robotic liver surgery, Vahrmeijer’s research is directly shaping the next generation of precision surgery, integrating 3D models and multimodal guidance into the operating room.

Research Focus

Key Achievements

8
H-Index
12
Papers
443
Total Citations
37
Avg Citations/Paper
🏆 Most Cited Paper
Image navigation as a means to expand the boundaries of fluorescence-guided surgery
85 citations · 2012
📈 Most Prolific Year: 2024 (2 Papers)
🤝 Key Collaborators: 128
🏛 Institutions: Leiden University Medical Center, Leiden University

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
Content generated · 15 days ago