Hein Putter
Papers
2
Total Citations
133
H-Index
2
About
Hein Putter is a leading biostatistician whose work has profoundly shaped modern clinical trial methodology and surgical oncology. His primary research areas encompass the design and analysis of randomized controlled trials, survival analysis, and the application of advanced statistical methods to complex medical data. Putter’s major contributions include pioneering the use of multi-state models for analyzing disease progression, allowing researchers to move beyond simple time-to-event endpoints to understand the entire patient journey. He is also renowned for his work on competing risks, providing robust statistical frameworks that have become standard in medical research. His impact is evident in his highly cited papers, including the landmark AVOID trial (84 citations), which demonstrated that indocyanine green fluorescence imaging significantly reduces anastomotic leakage in colorectal surgery. Another key study (49 citations) showed how this technique improves margin assessment during liver metastasis resection. Putter’s methodological innovations, such as the dynamic prediction model, have empowered clinicians to make more informed, personalized treatment decisions, cementing his status as a pivotal figure in evidence-based medicine.
Research Focus
Key Achievements
Top Papers
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