Henricus J.M. Handgraaf
Papers
1
Total Citations
84
H-Index
1
About
Henricus J.M. Handgraaf is a leading figure in surgical oncology, with a primary focus on improving outcomes in minimally invasive colorectal surgery through advanced intraoperative imaging. His most impactful work centers on the clinical application of near-infrared fluorescence imaging using indocyanine green to assess bowel perfusion in real time. As the principal investigator of the landmark AVOID trial—a multicentre, randomised, controlled, phase 3 study published in 2024—Handgraaf demonstrated that this technology significantly reduces the risk of anastomotic leakage, one of the most feared complications in colorectal surgery. With 84 citations already, this trial has rapidly become a cornerstone reference in the field. Beyond this, his research has advanced the use of fluorescence-guided surgery for sentinel lymph node mapping and tumor margin assessment. Handgraaf’s contributions bridge the gap between experimental imaging techniques and routine clinical practice, offering surgeons a reliable, non-invasive tool to enhance decision-making. His work is widely cited and has influenced surgical protocols internationally, marking him as a key innovator in precision surgery and patient safety.
Research Focus
Key Achievements
Top Papers
- 1