Sherry L. Morissette
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1
Total Citations
152
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About
Sherry L. Morissette is a pioneering figure in solid-state chemistry and pharmaceutical materials science, best known for her transformative work in high-throughput crystallization and polymorph screening. Her research focuses on understanding and controlling the solid forms of active pharmaceutical ingredients, which is critical for drug stability, solubility, and bioavailability. Morissette’s most cited work, "Iterative High-Throughput Polymorphism Studies on Acetaminophen and an Experimentally Derived Structure for Form III" (2002, 152 citations), introduced the groundbreaking CrystalMax platform—an integrated system of design software, robotic dispensing, and microanalytics capable of running thousands of crystallization experiments. This innovation enabled the discovery of acetaminophen’s elusive Form III, demonstrating how automation can systematically map polymorph landscapes. Her contributions have fundamentally advanced the field, providing researchers with tools to efficiently identify and characterize solid forms, thereby reducing development risks in pharmaceuticals. Morissette’s work has been widely adopted, influencing both academic research and industrial practices in drug formulation. Her legacy lies in bridging high-throughput experimentation with fundamental solid-state chemistry, making her a key figure in modern materials discovery.
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