Matthew L. Peterson
Papers
1
Total Citations
152
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1
About
Matthew L. Peterson is a leading figure in solid-state chemistry and pharmaceutical materials science, renowned for pioneering high-throughput crystallization methodologies. His most impactful work centers on the discovery and characterization of polymorphs—different crystal forms of the same compound—which are critical for drug development and intellectual property. Peterson's landmark 2002 study, with 152 citations, introduced CrystalMax, a revolutionary high-throughput platform integrating design software, robotic dispensing, and microanalytics. Using this system, he prepared and characterized three crystal forms of acetaminophen, including the elusive Form III, whose structure had long resisted experimental determination. This work demonstrated how automated, iterative screening can rapidly map polymorph landscapes, transforming how researchers approach solid-form discovery. Beyond this, Peterson has contributed to understanding crystallization kinetics and the stability of metastable forms, impacting both academic research and industrial formulation. His achievements include advancing robotic tools that enable thousands of experiments in parallel, significantly accelerating the pace of polymorphism studies. For students and researchers, Peterson’s work exemplifies how engineering and chemistry converge to solve fundamental problems in materials science.
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Top Papers
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