Martin LeQuesne
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1
Total Citations
152
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About
Martin LeQuesne is a leading figure in solid-state chemistry and pharmaceutical materials science, best known for pioneering high-throughput crystallization methodologies. His most impactful work, the 2002 study "Iterative High-Throughput Polymorphism Studies on Acetaminophen and an Experimentally Derived Structure for Form III," has garnered 152 citations and revolutionized how researchers explore crystal forms. In this landmark paper, LeQuesne introduced the CrystalMax platform—an integrated system combining design software, robotic sample handling, and high-throughput microanalytics capable of running thousands of experiments. This innovation enabled the discovery and structural characterization of acetaminophen Form III, a previously elusive polymorph, demonstrating that systematic, automated screening could uncover hidden solid forms critical for drug development and intellectual property. LeQuesne's contributions have had a lasting impact on pharmaceutical R&D, accelerating polymorph screening and reducing time-to-market for new medications. His work remains a cornerstone for researchers in crystal engineering and formulation science, showcasing how iterative, data-driven approaches can solve complex problems in molecular materials.
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