Julie Monagle
Papers
1
Total Citations
152
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About
Julie Monagle is a pioneering figure in solid-state chemistry and pharmaceutical materials science, best known for her transformative work in high-throughput crystallization and polymorphism. Her research focuses on understanding and controlling the crystal forms of active pharmaceutical ingredients, a critical area for drug development and manufacturing. Monagle's most cited paper, "Iterative High-Throughput Polymorphism Studies on Acetaminophen and an Experimentally Derived Structure for Form III" (2002, 152 citations), introduced the CrystalMax platform—a groundbreaking system integrating design software, robotic dispensing, and high-throughput microanalytics. This work enabled the rapid screening of thousands of crystallization conditions, leading to the discovery of a previously unknown third polymorph of acetaminophen. By demonstrating how automated, iterative experimentation can uncover elusive crystal forms, Monagle's contributions have significantly advanced the efficiency and reliability of polymorph screening in the pharmaceutical industry. Her achievements underscore the power of combining robotics with materials science, making her a key innovator in accelerating drug formulation and ensuring product stability.
Research Focus
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Top Papers
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