Serafina Valente

Azienda Ospedaliero-Universitaria Careggi

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About

Dr. Serafina Valente is a pioneering figure in radiation oncology, whose work has fundamentally reshaped the treatment of cardiac malignancies. Her primary research focuses on the application of stereotactic body radiotherapy (SBRT) for complex thoracic and cardiac tumors, where she has championed the use of advanced technologies like the CyberKnife system to overcome traditional radiobiological and technical limitations. Her landmark 2015 paper, "Stereotactic Body Radiotherapy with Cyberknife for Cardiac Malignancies," which has garnered 23 citations, established a critical proof-of-concept for delivering focused, high-dose radiation to the heart, a historically challenging anatomical site. This contribution has opened a new, non-invasive frontier for patients with primary and secondary cardiac tumors who previously had few viable options. Dr. Valente’s work is distinguished by its rigorous integration of radiobiological principles with cutting-edge delivery techniques, demonstrating that precision and safety can coexist even in the most sensitive of organs. Her research continues to inspire a generation of oncologists to push the boundaries of SBRT, offering renewed hope for patients with inoperable cardiac disease.