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About

Monica Mangoni is a leading clinical researcher in radiation oncology, specializing in stereotactic body radiotherapy (SBRT) and robotic radiosurgery for both oncologic and cardiac applications. Her work has been instrumental in advancing preoperative partial breast irradiation (PBI), as demonstrated by her pivotal phase II ROCK trial (NCT03520894), which established the feasibility and safety of preoperative robotic radiosurgery for early breast cancer—a study that has garnered 29 citations since 2022. Mangoni has also made significant contributions to the treatment of cardiac malignancies, showing that CyberKnife-based SBRT can safely deliver focused, high-dose radiation to cardiac tumors, a historically challenging area. Her research on abdominal lymph node metastases further underscores her expertise in image-guided SBRT, with 17 citations for her work demonstrating effective local control across diverse primary cancers. Through these contributions, Mangoni has helped expand the boundaries of non-invasive, high-precision radiotherapy, offering new treatment options for patients with breast, cardiac, and metastatic diseases. Her work continues to shape clinical practice and inspire further investigation into the role of stereotactic techniques in oncology.