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About

Pierluigi Bonomo is a leading radiation oncologist whose research centers on stereotactic body radiotherapy (SBRT) and robotic radiosurgery, particularly for treating recurrent and metastatic cancers. His major contributions lie in demonstrating the safety and efficacy of re-irradiation using robotic stereotactic techniques for patients with recurrent prostate cancer, as detailed in his most-cited work (50 citations). He has also advanced the application of CyberKnife-based SBRT for challenging sites, including cardiac malignancies and liver oligometastases from colorectal cancer, as well as abdominal lymph node metastases. Bonomo’s work has been instrumental in expanding the role of high-precision, image-guided radiation therapy beyond traditional boundaries, offering new treatment options for patients with limited disease burden or prior irradiation. His studies consistently report promising local control rates with acceptable toxicity, helping to establish SBRT as a viable strategy in oligometastatic disease. With over 100 total citations across his key publications, Bonomo’s research continues to shape clinical practice in stereotactic radiotherapy, providing critical evidence for treating complex and previously irradiated tumor sites.