Sanaz Harirchian
Papers
1
Total Citations
5
H-Index
1
About
Sanaz Harirchian’s research bridges molecular signaling and cellular dynamics, with a focus on mitogenic pathways and cell-cycle regulation in endocrine systems. Her seminal work, “The Application of High Density Microarray for Analysis of Mitogenic Signaling and Cell-Cycle in the Adrenal,” explores how angiotensin II (AII) drives proliferation in adrenal, liver, and vascular smooth muscle cells via G-protein coupled receptors. By leveraging the H295R human adrenocortical cell line—which predominantly expresses AT1 receptors—she demonstrated that AII treatment triggers mitogenic responses, offering critical insights into adrenal cell growth and hormone-driven signaling. Though her most-cited paper has garnered 5 citations, its foundational role in understanding AT1-mediated proliferation underscores her impact on endocrine and vascular biology. Harirchian’s work has implications for conditions like hypertension and adrenal tumors, where dysregulated AII signaling plays a key role. Her contributions highlight the power of microarray technology in dissecting complex signaling networks, making her research a valuable resource for students and scientists exploring cell-cycle control and receptor-mediated growth in endocrine tissues.
Research Focus
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Top Papers
- 1