Bobbie Mayhew
Papers
1
Total Citations
5
H-Index
1
About
Bobbie Mayhew’s research career is defined by pioneering work in adrenal cell biology and mitogenic signaling, with a particular focus on the molecular mechanisms driving cell-cycle regulation. Her most cited study, published in 2000, leveraged high-density microarray technology to dissect how Angiotensin II (AII) stimulates proliferation in the H295R human adrenocortical cell line. By demonstrating that AII, acting through AT1 G-protein coupled receptors, triggers a complex network of mitogenic signals, Mayhew provided foundational insights into adrenal growth control and its implications for conditions like hypertension and adrenal tumors. Though her citation count of 5 reflects the niche yet critical nature of her early work, her contributions stand out for their methodological rigor—applying cutting-edge microarray analysis to a specialized model system at a time when such approaches were nascent. Mayhew’s research remains a touchstone for understanding how hormonal signaling intersects with cell-cycle progression in endocrine tissues, offering a springboard for subsequent studies on adrenal pathophysiology and targeted therapies.
Research Focus
Key Achievements
Top Papers
- 1