Ph. Hubert
Papers
2
Total Citations
41
H-Index
2
About
Ph. Hubert is a pharmaceutical analytical chemist whose research has made significant contributions to the development of automated and sensitive bioanalytical methods for drug analysis in human plasma. Working primarily through the late 1980s and 1990s, Hubert pioneered innovative approaches combining sample preparation techniques with high-performance liquid chromatography (HPLC) to advance pharmacokinetic and clinical research. Hubert's most influential work, published in 1990 and accumulating 22 citations, introduced a fully automated method for determining indomethacin in human plasma by coupling liquid-solid extraction on disposable cartridges with HPLC — a significant methodological advancement that streamlined bioanalytical workflows and improved reproducibility. Building on this foundation, Hubert later expanded into stereochemical analysis, with a 1997 study garnering 19 citations for developing an enantioselective method to determine oxprenolol in plasma using on-line dialysis paired with chiral liquid chromatography. This work addressed the growing recognition that drug enantiomers can differ substantially in pharmacological activity. Together, these contributions reflect Hubert's expertise in analytical method development, automation, and chiral separations — tools that remain essential for modern drug monitoring and pharmaceutical research.
Research Focus
Key Achievements
Top Papers
- 1
- 2