B. Toussaint
Papers
2
Total Citations
50
H-Index
2
About
B. Toussaint is a specialist in bioanalytical chemistry, with a focus on the development of automated sample preparation techniques for therapeutic drug monitoring. Her major contributions lie in pioneering the on-line coupling of dialysis with high-performance liquid chromatography (HPLC), a method that significantly streamlines the analysis of drugs in biological fluids. Her most cited work, "Automated determination of verapamil and norverapamil in human plasma" (1996, 31 citations), demonstrates a robust, fully automated system that reduces manual handling and improves throughput for quantifying cardiovascular drugs. She further advanced the field by applying this technique to chiral separations, as seen in her 1997 paper on oxprenolol (19 citations), which enabled the enantioselective determination of beta-blockers in human plasma. These innovations are notable for their practical impact on clinical and pharmaceutical analysis, offering a cleaner, more efficient alternative to traditional liquid-liquid extraction. Toussaint’s work remains a reference for researchers developing high-throughput, automated methods for drug quantification in complex matrices.
Research Focus
Key Achievements
Top Papers
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