Matthew M. Benning
Papers
1
Total Citations
26
H-Index
1
About
Matthew M. Benning is a pioneer in the automation of structural biology, whose work has fundamentally advanced high-throughput protein crystallography. His key research areas include robotic crystal harvesting, cryo-mounting automation, and the development of integrated pipelines for macromolecular crystallography. Benning’s major contribution is the creation of a universal micromanipulation robot for operator-assisted harvesting of protein crystals, a breakthrough that bridges the gap between fully automated crystallization setups and the manual, labor-intensive step of crystal mounting. This innovation, detailed in his most-cited paper (2007, 26 citations), dramatically improves efficiency and reproducibility in structural determination. By enabling computer-assisted robotic handling of delicate crystals, his work has accelerated the pace of structural genomics and drug discovery. Benning’s achievements are notable for their practical impact, directly addressing a critical bottleneck in the crystallographic workflow and inspiring further automation in synchrotron beamlines and laboratory robotics. His contributions continue to shape how researchers approach the physical manipulation of protein crystals for X-ray diffraction.
Research Focus
Key Achievements
Top Papers
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