Papers
2
Total Citations
37
H-Index
2
About
P. Carman is a pioneer in the automation of structural biology, specializing in high-throughput protein crystallography. Their major contributions center on overcoming the critical bottleneck of crystal harvesting—the delicate manual step of mounting protein crystals for X-ray diffraction. Carman’s most influential work, "Operator-assisted harvesting of protein crystals using a universal micromanipulation robot" (2007, 26 citations), introduced a robotic system that seamlessly integrates with existing crystallization pipelines, enabling computer-assisted, reproducible harvesting. This innovation dramatically reduces human error and accelerates throughput, bridging the gap between automated crystallization setup and data collection. A follow-up study (2007, 11 citations) critically evaluates the trade-offs of such automation, questioning whether robotic harvesting is a necessary solution or "instrumentation overkill." By addressing both the technical feasibility and practical limitations, Carman has shaped the discourse on laboratory automation in structural biology. Their work remains a foundational reference for researchers seeking to streamline the crystallography workflow, demonstrating a balanced perspective that advances the field while acknowledging real-world constraints.
Research Focus
Key Achievements
Top Papers
- 1
- 2