Mark G. van Vledder

Erasmus University Rotterdam, Johns Hopkins University

Papers

Total Citations

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About

Mark G. van Vledder is a leading researcher in image-guided interventions and surgical oncology, with a focus on advancing minimally invasive techniques for liver cancer treatment. His work bridges engineering and clinical practice, particularly in robotic needle steering and intraoperative imaging. His most cited paper (90 citations) explores the behavior of tip-steerable needles in ex vivo and in vivo tissue, demonstrating how computer-controlled curved insertions can improve the precision and effectiveness of biopsies and ablation procedures—a breakthrough with direct implications for reducing patient trauma and improving outcomes. Van Vledder also developed a large animal model for hepatic pseudotumors, enabling realistic testing of image-guided interventional and surgical tools. His contributions have been instrumental in translating robotic needle steering from concept toward clinical reality, addressing key challenges in tissue deformation and real-time guidance. With a citation count exceeding 90 for his flagship work, van Vledder’s research is highly regarded for its practical impact, offering students and researchers a clear example of how engineering innovation can solve pressing clinical problems in oncology.