Marie Locard‐Paulet

Centre National de la Recherche Scientifique

Papers

Total Citations

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About

Dr. Marie Locard-Paulet is a leading expert in structural proteomics and biophysics, with a particular focus on advancing Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS). Her major contribution is the development of **HDX-Viewer**, an interactive 3D visualization tool that revolutionized how researchers analyze and interpret HDX-MS data. This software bridges a critical gap between automated sample preparation and meaningful structural interpretation, making HDX-MS more accessible for ligand binding studies and epitope mapping in both academia and the biopharmaceutical industry. Her work has been cited over 34 times, reflecting its practical impact on structural biology workflows. Beyond this flagship tool, Dr. Locard-Paulet has made significant contributions to understanding protein dynamics and interactions, particularly in the context of drug discovery. Her achievements include developing computational methods that integrate experimental data with structural models, enabling researchers to visualize conformational changes in proteins with unprecedented clarity. Her research continues to shape how scientists study protein folding, stability, and molecular recognition, making her a pivotal figure in the evolution of biophysical characterization techniques.