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About

Madeleine M. Lowery is a leading figure in neural engineering and neuromuscular modeling, whose work bridges fundamental neurophysiology with transformative clinical applications. Her most impactful contribution is the development of **targeted muscle reinnervation (TMR)** , a novel neural-machine interface that decodes motor control signals to power advanced prosthetic limbs. Her seminal 2007 paper on this topic, cited over 216 times, demonstrated how re-routing residual nerves to new muscle targets enables intuitive, high-fidelity control of artificial arms—a breakthrough that has reshaped upper-limb prosthetics. Lowery’s research also advances the **Consensus for Experimental Design in Electromyography (CEDE)** project, where she leads efforts to standardize how surface EMG signals are used to estimate muscle force, a critical challenge in biomechanics and rehabilitation. Her work integrates computational modeling, signal processing, and experimental validation, providing non-invasive tools to decode the neural drive to muscles. With a career spanning over two decades, Lowery’s contributions have not only deepened our understanding of motor control but also delivered tangible technologies that restore function and independence for individuals with limb loss. Her research remains a cornerstone for students and engineers seeking to merge neuroscience with engineering for human benefit.