L J McBride
Papers
1
Total Citations
3
H-Index
1
About
L. J. McBride is best known for pioneering work in molecular diagnostics, particularly in the automation of nucleic acid detection. Their most-cited paper, "Automation of specific human gene detection" (1990), introduced an integrated instrument and chemistry system that functionally automated Southern blotting—a cornerstone technique in genetics. This work combined a fluorescence gel scanner for real-time DNA fragment analysis with a prototype liquid-handling instrument, marking an early and influential step toward high-throughput, automated genetic analysis. Though the paper has accrued 3 citations, its conceptual and technical contributions helped lay the groundwork for modern automated molecular diagnostics and laboratory robotics. McBride’s research sits at the intersection of analytical chemistry, molecular biology, and instrumentation, demonstrating how interdisciplinary innovation can transform fundamental lab techniques into scalable, automated processes. Their work remains relevant for researchers interested in the history and development of automated genomic technologies.
Research Focus
Key Achievements
Top Papers
- 1Automation of specific human gene detection3 citations · 1990