Jens Moeller
Papers
1
Total Citations
58
H-Index
1
About
Jens Moeller is a pioneering researcher at the intersection of mechanobiology and immunology, with a primary focus on the physical mechanisms governing phagocytosis—the process by which immune cells engulf pathogens. His most cited work, "Robotically controlled microprey to resolve initial attack modes preceding phagocytosis" (2017, 58 citations), introduces a groundbreaking 5D microrobotic manipulation system (5D-MTS) that probes both translational and rotational attack modes of macrophages with unprecedented spatial and temporal resolution. Moeller’s major contribution lies in revealing that macrophages fail to realign their prey when mechanically constrained, directly inhibiting successful uptake—a discovery that challenges conventional biochemical models of immune recognition. This proof-of-concept study not only illuminates the initial physical steps of phagocytosis but also establishes a versatile platform for exploring a wide array of mechanobiology questions, from cell migration to tissue mechanics. Moeller’s work bridges engineering and biology, offering researchers a powerful tool to dissect how cells sense and respond to mechanical forces, with profound implications for understanding immune dysfunction and designing targeted therapies.
Research Focus
Key Achievements
Top Papers
- 1