Jason Chia‐Hsien Cheng
National Taiwan University Hospital, National Taiwan University
Papers
2
Total Citations
20
H-Index
2
About
Jason Chia‐Hsien Cheng is a leading researcher in tumor immunology, with a focused expertise on the role of natural killer (NK) cells in prostate cancer (PCa) progression and post-surgical outcomes. His major contributions center on elucidating how the immune microenvironment influences cancer recurrence, specifically demonstrating that lower postoperative NK cell activity is a critical biomarker for positive surgical margins after radical prostatectomy—a finding with over 14 citations that has reshaped understanding of immune surveillance in PCa. Dr. Cheng further advanced the field by identifying NKG2A and circulating extracellular vesicles as key regulators of NK cell function, showing how these vesicles in peripheral blood modulate immune responses post-surgery. His work, cited more than 20 times, bridges the gap between basic immunology and clinical oncology, offering novel insights into how the inflammatory milieu and EV-mediated signaling drive cancer progression. By highlighting NK cell subset distribution patterns and their prognostic value, Dr. Cheng’s research provides a foundation for developing immune-based therapeutic strategies to improve outcomes for prostate cancer patients, marking him as a pivotal figure in translational cancer immunology.
Research Focus
Key Achievements
Top Papers
- 1
- 2