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About

Guihuai Wang is a pioneering researcher at the intersection of biomedical optics and robotic surgery, whose work is revolutionizing intraoperative imaging for neurosurgery. His key research areas include optical coherence tomography angiography (OCTA), robotic-assisted microvascular imaging, and real-time tumor grading. Wang’s major contribution is the development of the Fast Adaptive Focus Tracking Robotic OCT (FACT-ROCT) system, a breakthrough that enables high-resolution, large-area microvascular imaging of irregular biological surfaces—such as the human spinal cord—during live surgery. His 2022 paper on whole-brain microvascular imaging using robot-assisted OCTA has garnered 23 citations, establishing a foundation for non-invasive, depth-resolved vascular mapping. More recently, his 2025 studies in *Advanced Science* (with 4 and 3 citations, respectively) demonstrate the clinical translation of this technology, allowing surgeons to grade spinal cord tumors in real time while visualizing microvasculature across wide fields. Wang’s work is notable for solving the longstanding trade-off between resolution and field size in OCT, and his robotic focus-tracking innovation promises to enhance precision in tumor resection, reduce surgical risks, and improve patient outcomes. His research stands at the forefront of merging robotics with optical imaging for next-generation surgical guidance.