Frans CT van der Helm
Papers
1
Total Citations
45
H-Index
1
About
Frans CT van der Helm is a leading figure in computational neuroscience and motor control, with a particular focus on the neural mechanisms underlying movement disorders. His research bridges experimental neurophysiology and mathematical modeling to understand how the brain coordinates movement and how this process breaks down in pathological conditions. One of his most notable contributions is the development of a computational model explaining fixed dystonia in Complex Regional Pain Syndrome (CRPS), a debilitating condition where approximately 25% of patients develop sustained, involuntary muscle contractions. His 2011 paper on this topic, which has garnered 45 citations, provides a mechanistic account linking dysfunctional GABAergic interneurons to the emergence of dystonic postures. Beyond this work, van der Helm has made seminal contributions to the study of sensorimotor integration, including the role of proprioceptive feedback and the neural control of arm movements. His work is characterized by a rigorous, interdisciplinary approach that integrates experimental data with computational theory, making him a key reference for students and researchers interested in the neural basis of movement and its disorders.
Research Focus
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Top Papers
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