Floor Hageman
Papers
1
Total Citations
32
H-Index
1
About
Floor Hageman is a cancer researcher whose work centers on DNA damage response mechanisms and the development of targeted radiosensitizers for cancer therapy. Her most cited study, published in 2017, identified a novel ATM inhibitor with cancer cell-specific radiosensitization activity, demonstrating how selective targeting of the ATM kinase can enhance the efficacy of radiotherapy while sparing normal tissues. This work, which has accumulated 32 citations, represents a significant contribution to the field of precision oncology, offering a strategy to improve treatment outcomes for patients with head and neck cancers and other solid tumors. Hageman's research bridges fundamental molecular biology and translational medicine, providing insights into how tumor-specific vulnerabilities can be exploited to overcome radioresistance. Her collaborative approach, working alongside experts in oncology, immunology, and chemical biology, underscores her commitment to developing more effective and less toxic cancer therapies. For students and researchers, Hageman's work exemplifies the power of mechanistic discovery in driving clinical innovation, highlighting the potential of ATM inhibitors as a promising avenue for enhancing the therapeutic index of radiotherapy.
Research Focus
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Top Papers
- 1