Amy J.C. Dohmen
Papers
1
Total Citations
32
H-Index
1
About
Amy J.C. Dohmen is a translational cancer researcher whose work focuses on head and neck oncology and the development of novel radiosensitization strategies. Her most cited study, "Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity" (2017, 32 citations), represents a significant contribution to the field of radiation oncology. In this collaborative work, Dohmen and her team identified a new inhibitor of the ATM kinase, a key DNA damage response protein, and demonstrated its ability to selectively enhance the radiosensitivity of cancer cells while sparing normal tissues. This discovery has important implications for improving the therapeutic ratio in radiotherapy, particularly for head and neck cancer patients. The paper, published during her tenure at the Department of Head and Neck Oncology, showcases her expertise in combining chemical biology with preclinical cancer models. Dohmen's research bridges fundamental DNA repair mechanisms with clinical applications, aiming to develop more effective and less toxic cancer treatments. Her work continues to influence the development of targeted radiosensitizers, making her a notable figure in the intersection of molecular oncology and radiation therapy.
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Top Papers
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