E.V. Blagova
Papers
3
Total Citations
86
H-Index
3
About
E.V. Blagova is a structural biologist whose research has made significant contributions to our understanding of protein architecture in pathogenic organisms, with a particular focus on *Bacillus anthracis*, the bacterium responsible for anthrax. Working within the Structural Proteomics in Europe (SPINE) initiative — a collaborative high-throughput structural genomics program — Blagova has been instrumental in determining high-resolution crystal structures of essential bacterial proteins, providing critical insights into potential therapeutic targets. Her most-cited work, the crystal structure of dihydrodipicolinate synthase (BA3935) from *B. anthracis* resolved at 1.94 Å, has garnered 47 citations and exemplifies her expertise in tackling enzymes encoded by essential genes — proteins with strong potential as antibiotic targets. Alongside collaborators from the York and Oxford laboratories, she contributed to a landmark high-throughput structural proteomics analysis of *B. anthracis* (27 citations), streamlining the pipeline from gene to structure. Her structural characterization of PurE (BA0288), an enzyme involved in nucleotide biosynthesis, further demonstrates her breadth within bacterial biochemistry. Blagova's work sits at the important intersection of structural biology and infectious disease research, offering foundational knowledge to those developing novel antimicrobial strategies.
Research Focus
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