Dominique Liger
Papers
2
Total Citations
43
H-Index
2
About
Dominique Liger is a leading figure in structural genomics, whose work has been instrumental in overcoming the bottlenecks of high-throughput protein crystallography. Her research focuses on developing open-source software solutions and optimization strategies to streamline the pipeline from gene to structure. Liger’s major contribution is the creation of *HalX*, an open-source Laboratory Information Management System (LIMS) designed to manage the complex data flow of structural biology projects. This tool, cited 28 times, provides a scalable framework for laboratories of all sizes, enabling efficient tracking of samples and experiments. Complementing this, her work on the South Paris Yeast Structural Genomics Project (cited 15 times) tackled the critical hurdle of crystal optimization. By demonstrating that automated nanodrop crystallization screens could be effectively standardized—a "one size fits all" approach—she helped transform a traditionally manual, artisanal process into a robust, high-throughput operation. Liger’s contributions have been vital in enabling the systematic structure determination that underpins modern drug discovery and our understanding of protein function.
Research Focus
Key Achievements
Top Papers
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