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About

Dolores J. Cahill is a molecular biologist and immunologist whose research has made significant contributions to the development of protein microarray technologies and their applications in medicine and diagnostics. Based at University College Dublin, Cahill has been instrumental in pioneering high-throughput proteomics approaches, particularly the use of protein and antibody arrays for disease profiling and biomarker discovery. Her most influential work, "Protein and antibody arrays and their medical applications" (2001), has garnered 286 citations and helped establish the conceptual framework for deploying protein microarrays in clinical and research settings. Building on this foundation, she applied these technologies to autoimmune disease research, notably profiling autoantigens in alopecia areata (75 citations) and optimizing autoantibody detection methods for conditions such as rheumatoid arthritis and cancer. Her work extending protein microarray platforms to infectious disease — particularly identifying novel diagnostic markers for *Neisseria meningitidis* (55 citations) — demonstrates the broad translational reach of her research. Cahill also contributed to the underlying molecular toolkit, developing yeast-based cDNA expression libraries enriched for open reading frames, enabling more efficient large-scale protein expression. Across her career, she has consistently bridged fundamental molecular biology with practical diagnostic innovation.