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Angelika Lueking is a pioneer in the development and application of protein microarray technology, a field she has helped shape since its earliest days. Her foundational work, including the highly influential 1999 paper "Protein Microarrays for Gene Expression and Antibody Screening" (435 citations), established the core methodologies for using these chips to analyze complex biological samples in parallel. She has been instrumental in advancing high-throughput techniques, such as generating cDNA expression libraries in yeast enriched for open reading frames, which streamlined the production of the thousands of proteins needed to populate these arrays. Dr. Lueking’s research has had a significant translational impact, particularly in immunology and dermatology. Her 2005 study, "Profiling of Alopecia Areata Autoantigens Based on Protein Microarray Technology" (75 citations), demonstrated the power of her approach by identifying novel autoantibody targets in an autoimmune disease. By creating protein chips for organisms ranging from *Arabidopsis* to humans, she has provided the scientific community with essential tools for large-scale antibody and serum screening, cementing her legacy as a key innovator in functional proteomics.