Clive Meredith
Papers
6
Total Citations
354
H-Index
6
About
Clive Meredith is a toxicologist specializing in the development and application of innovative *in vitro* testing methodologies for assessing the biological and toxicological effects of tobacco and e-cigarette aerosols. His research has been instrumental in establishing scientifically rigorous, physiologically relevant alternatives to traditional testing approaches, with a particular focus on respiratory toxicology and genotoxicity assessment. Meredith's most impactful contribution — cited 134 times — introduced a landmark 3D reconstructed human airway tissue model for evaluating e-cigarette aerosol cytotoxicity, helping to fill a critical regulatory and scientific gap as vaping products emerged globally. Complementing this work, he has systematically advanced bacterial mutagenicity (Ames assay) methodologies adapted for complex aerosol exposure systems, including multi-strain approaches and inter-laboratory comparisons that have strengthened reproducibility across the field. A recurring theme in his portfolio is the optimization and standardization of the Vitrocell® VC 10 Smoking Robot platform, with studies quantifying particle deposition dynamics that underpin reliable toxicological comparisons between tobacco and next-generation products. With over 350 cumulative citations across his key publications, Meredith's work has meaningfully shaped regulatory science and harm-reduction research, providing the methodological foundations that laboratories worldwide now use to evaluate inhaled product safety.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3
- 4
- 5
- 6