Joanne Kilford
Papers
2
Total Citations
71
H-Index
2
About
Dr. Joanne Kilford is a leading toxicologist whose research has fundamentally advanced the methodology for assessing the genotoxicity of complex aerosols, particularly mainstream cigarette smoke. Her work centers on developing and validating robust, aerosol-based exposure systems to replace outdated, less physiologically relevant testing methods. Dr. Kilford’s major contribution lies in her pioneering adaptation of the bacterial reverse-mutation (Ames) assay for use with whole smoke. Her most-cited paper (41 citations) established a multi-strain approach using the Vitrocell® VC 10 Smoking Robot, systematically evaluating strains like TA97 and TA104 to create a more comprehensive mutagenic profile. Her 2014 foundational paper (30 citations) addressed the critical lack of standardized methods for testing gaseous mixtures, providing a validated protocol that bridges the gap between regulatory requirements and real-world exposure. This work has been instrumental in setting new standards for the tobacco industry and regulatory toxicology. By enabling more accurate genotoxicity assessments of cigarette smoke, Dr. Kilford’s research directly supports public health initiatives and the evaluation of reduced-risk products.
Research Focus
Key Achievements
Top Papers
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