M. Hollings
Papers
3
Total Citations
111
H-Index
3
About
M. Hollings has established a focused research presence at the intersection of toxicology, mutagenicity testing, and tobacco science, with particular expertise in the genotoxic assessment of cigarette and electronic cigarette smoke. Working primarily with the Ames assay — a foundational bacterial mutagenicity test — Hollings has made significant contributions to refining and expanding methodological frameworks for evaluating the harmful potential of inhaled aerosols under standardized conditions. Among Hollings' most influential contributions is a 2016 study (57 citations) demonstrating that e-cigarette aerosol collected matter was non-mutagenic in established Ames assay strains TA98 and TA100, offering important comparative data against traditional cigarette smoke. A complementary 2015 paper (41 citations) advanced the field by systematically evaluating multiple Salmonella typhimurium strains — including TA97, TA102, and TA104 — in combination with the Vitrocell® VC10 Smoking Robot, filling a notable gap in the literature. A 2019 investigation further refined whole smoke dosimetry techniques using air-liquid and air-agar interface platforms, strengthening the translational validity of in vitro smoke exposure models. Collectively, Hollings' work has helped modernize regulatory toxicology approaches, providing the scientific community with more robust, reproducible tools for assessing tobacco and next-generation product risks.
Research Focus
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Top Papers
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