Brian M. Keyser
Papers
2
Total Citations
23
H-Index
2
About
Brian M. Keyser is a leading researcher in the field of in vitro toxicology, with a specialized focus on the dosimetry and biological assessment of combustible tobacco product emissions. His major contributions center on advancing the methodology for whole smoke exposure, moving beyond traditional, less representative partitioned analyses of total particulate matter and gas vapor phase. Keyser’s work has been instrumental in validating and refining the use of the VITROCELL® VC10® smoke exposure system, a cutting-edge platform that enables air-liquid and air-agar interface exposures to mimic in vivo conditions. His highly cited 2019 study (13 citations) systematically investigated multiple whole smoke dosimetry techniques, while his foundational 2018 paper (10 citations) developed a quantitative method for dose assessment in these in vitro evaluations. Together, these achievements have established a more physiologically relevant standard for assessing the cytotoxic and genotoxic potential of tobacco products, directly impacting regulatory and product stewardship science. Keyser’s research is essential reading for toxicologists and inhalation scientists seeking robust, reproducible methods for smoke exposure studies.
Research Focus
Key Achievements
Top Papers
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