Christoph H. Borchers
University of Victoria, University of North Carolina at Chapel Hill, McGill University
Papers
4
Total Citations
193
H-Index
4
About
Christoph H. Borchers is a distinguished analytical chemist and proteomics researcher whose work has fundamentally advanced the field of targeted protein quantification and biomarker detection. His research centers on mass spectrometry-based approaches, with particular expertise in developing innovative methodologies for clinical diagnostics and plasma proteomics. Borchers is perhaps best known for his pioneering contributions to SISCAPA (Stable Isotope Standards and Capture by Anti-Peptide Antibodies) technology, where his work on magnetic bead-based peptide enrichment using a novel rotary bead trap device has garnered over 140 citations, becoming a cornerstone reference for researchers pursuing antibody-based peptide capture workflows. His development of immuno-MALDI (iMALDI) assays represents another landmark achievement, enabling highly accurate quantification of targeted peptides from volume-restricted clinical samples — work that has direct implications for diagnosing secondary hypertension through plasma renin activity measurement. His earlier methodological contributions include improving protein identification from low-abundance samples using unstained gel workflows combined with MALDI tandem mass spectrometry. Collectively, Borchers' research portfolio reflects a consistent commitment to translating sophisticated mass spectrometric techniques into clinically meaningful diagnostic tools, making him a highly influential figure in both proteomics and precision medicine communities.
Research Focus
Key Achievements
Top Papers
- 1SISCAPA Peptide Enrichment on Magnetic Beads Using an In-line Bead Trap Device143 citations · 2009
- 2
- 3Improved Protein Identification through the Use of Unstained Gels6 citations · 2005
- 4