Celina Ang
Papers
2
Total Citations
145
H-Index
2
About
Celina Ang is a pioneering clinician-scientist whose work lies at the intersection of precision oncology and rare cancers. She has made groundbreaking contributions to personalized cancer therapy by developing innovative, real-time drug screening platforms. Her landmark 2019 study (107 citations) introduced a personalized platform using patient-derived organoids, or "hindguts," to identify a novel combination therapy—trametinib plus zoledronate—for a patient with KRAS-mutant metastatic colorectal cancer. This robotics-based screen led to a dramatic 11-month partial response, demonstrating the power of tailoring treatments to individual tumor biology. In a subsequent 2021 study (38 citations), she extended this approach to adenoid cystic carcinoma (ACC), a rare salivary gland cancer with limited treatment options. Using a Drosophila-based platform, she identified a personalized therapy for a patient, offering new hope for this challenging disease. Her work not only showcases the potential of functional precision medicine but also provides a scalable framework for treating patients with refractory cancers. Dr. Ang’s research is a testament to the transformative impact of combining innovative technology with compassionate, patient-centered care.
Research Focus
Key Achievements
Top Papers
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