Patricia Taik

Sema4 (United States)

Papers

2

Total Citations

145

H-Index

2

About

Patricia Taik is a pioneering translational researcher whose work bridges rare cancer genomics and personalized medicine using innovative model systems. Her key research areas include precision oncology, rare tumor biology, and the development of personalized therapeutic platforms. Taik’s major contributions center on using Drosophila-based avatars to identify effective drug combinations for patients with limited treatment options. Her landmark 2019 study, cited over 100 times, introduced a robotics-based screening platform that identified trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer, resulting in a strong partial response lasting 11 months. She further demonstrated the power of this approach in a 2021 study on adenoid cystic carcinoma, a rare salivary gland cancer with poor outcomes, where her platform uncovered a novel personalized therapy. Taik’s work has reshaped how clinicians approach treatment-refractory cancers, offering a scalable, cost-effective method to match patients with targeted therapies. Her achievements highlight the potential of cross-species modeling to accelerate precision oncology, making her a leading voice in the fight against rare and difficult-to-treat malignancies.

Research Focus

Key Achievements

2
H-Index
2
Papers
145
Total Citations
73
Avg Citations/Paper
🏆 Most Cited Paper
A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer
107 citations · 2019
📈 Most Prolific Year: 2019 (1 Papers)
🤝 Key Collaborators: 31
🏛 Institutions: Sema4 (United States)

Top Papers

  1. 1
  2. 2

Key Collaborators

Contact & Links

Available for collaboration
Content generated · 13 days ago