Bruno Streel
Papers
4
Total Citations
181
H-Index
4
About
Bruno Streel is an analytical chemist whose research has made significant contributions to the field of bioanalytical method development, particularly in the quantification of pharmaceutical compounds and their metabolites in human plasma. His work centers on advancing liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) and solid-phase extraction techniques to enable precise, reliable drug analysis in biological matrices. Streel's most impactful contribution is his 2000 study on the enantiomeric determination of tramadol and its primary metabolite O-desmethyltramadol, which has garnered 82 citations and remains a key reference for researchers working on chiral separation in pharmacokinetic studies. His broader portfolio demonstrates consistent innovation across multiple drug classes, including lipid-lowering agents such as fenofibric acid (46 citations), cardiovascular drugs like nifedipine and dehydronifedipine (43 citations), and vasodilatory compounds such as molsidomine. Together, these publications underscore his expertise in developing robust, sensitive analytical methods that support drug development and clinical pharmacology research. His work has provided the bioanalytical community with validated methodologies that continue to inform therapeutic drug monitoring and pharmacokinetic investigations worldwide.
Research Focus
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