Renilde Sibenaler
Papers
2
Total Citations
53
H-Index
2
About
Renilde Sibenaler is a distinguished bioanalytical chemist whose work has advanced the precise quantification of cardiovascular drugs in human plasma. Her primary research focuses on developing and validating highly sensitive liquid chromatography–tandem mass spectrometry (LC-MS/MS) methods for therapeutic drug monitoring and pharmacokinetic studies. Her most influential contribution, the simultaneous determination of nifedipine and its active metabolite dehydronifedipine in human plasma, has garnered 43 citations, reflecting its foundational role in calcium channel blocker analysis. This method enabled accurate assessment of drug metabolism and bioavailability, directly impacting clinical dosing strategies. Sibenaler also pioneered an LC-MS/MS approach for molsidomine and its active metabolite, demonstrating her versatility in handling labile compounds. Her work is characterized by rigorous validation protocols and practical applicability, making her methods essential tools for pharmaceutical research. With a career spanning the late 1990s, Sibenaler’s contributions remain cited in contemporary studies on drug–drug interactions and bioequivalence, underscoring her lasting influence on analytical pharmacology and patient safety.
Research Focus
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Top Papers
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