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About

Baoquan Ding is a pioneer at the intersection of DNA nanotechnology and biomedicine, best known for engineering intelligent, programmable nanodevices that operate within living systems. His most celebrated contribution is the development of a DNA nanorobot that functions as a cancer therapeutic in response to a molecular trigger in vivo—a landmark study with over 1,480 citations that demonstrated the first autonomous, logic-gated nanorobot capable of delivering payloads directly to tumors in living animals. This work, published in *Nature Biotechnology*, represents a paradigm shift in targeted drug delivery and has inspired a generation of researchers in nanomedicine. Ding’s foundational contributions also include the precise placement and operation of a DNA robot arm within a 2D crystalline substrate, a critical step toward functional DNA-based nanorobotics. More recently, he has advanced logic-gated plasmonic nanodevices through DNA-templated assembly, merging structural DNA nanotechnology with optical signal processing. His work consistently bridges fundamental molecular engineering with real-world applications, earning him recognition as a leader in the field. With a career spanning over two decades, Ding’s research continues to push the boundaries of what DNA-based machines can achieve, from targeted therapeutics to smart diagnostic platforms.