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Antje Knopf is a leading figure in the field of precision radiotherapy, with a primary research focus on managing intrafraction motion during external beam treatment. Her work addresses a critical challenge in radiation oncology: the constant movement of internal anatomy due to respiration, cardiac activity, and other physiological processes. Knopf’s major contribution lies in the development and clinical implementation of real-time motion monitoring systems, which allow for dynamic tracking of tumors during dose delivery. Her most-cited paper, "Real-time intrafraction motion monitoring in external beam radiotherapy" (2019, 219 citations), serves as a foundational reference for the field, synthesizing techniques to improve treatment accuracy and spare healthy tissues. She has also advanced robustness evaluation in intensity-modulated proton therapy (IMPT) for head and neck cancers, as seen in her 2019 work on dose accumulation. Through her research, Knopf has significantly enhanced the safety and efficacy of modern radiotherapy, directly impacting clinical protocols for treating moving tumors. Her contributions are essential reading for students and researchers seeking to understand motion management in radiation oncology.