Alice Robson
Papers
1
Total Citations
20
H-Index
1
About
Alice Robson is a structural biologist whose work has advanced the field of protein crystallography, with a particular focus on optimizing crystallization methods. Her key research areas include protein structure determination, biophysical characterization, and the development of innovative crystallization techniques. Robson’s most notable contribution is the introduction of random microseed matrix screening (rMMS), a powerful method that enhances the success rate of protein crystallization by introducing seed crystals into random screening conditions. This technique, detailed in her 2013 paper (20 citations), helps researchers navigate the metastable zone of a protein’s phase diagram, yielding higher-quality crystals and additional crystallization leads. Her work has proven invaluable for structural genomics and drug discovery, where obtaining well-diffracting crystals remains a major bottleneck. By providing a practical, reproducible approach to improve crystallization outcomes, Robson has empowered researchers to tackle challenging proteins, ultimately accelerating the pace of structural biology. Her contributions continue to influence best practices in the field, making her a key figure in the ongoing effort to solve the three-dimensional structures of biologically and medically important macromolecules.
Research Focus
Key Achievements
Top Papers
- 1