Structural genomics

A cell-free protein synthesis system for high-throughput proteomics

Tatsuya Sawasaki, Tomio Ogasawara, Ryo Morishita, Yaeta Endo

Citations: 523 • 2002

Keynote review: Structural biology and drug discovery

Miles Congreve, Christopher W. Murray, Tom L. Blundell

Citations: 340 • 2005

Protein expression systems for structural genomics and proteomics

Shigeyuki Yokoyama

Citations: 256 • 2003

Robotic Cloning and Protein Production Platform of the Northeast Structural Genomics Consortium

Thomas Acton, Kristin C. Gunsalus, Rong Xiao, Li Chung, James M. Aramini, Michael Baran, Yiwen Chiang, Teresa Climent, B. Cooper, Natalia G. Denissova, Shawn M. Douglas, J.K. Everett, Chi Kent Ho, Daphne Macapagal, P.K. Rajan, Ritu Shastry, Liang-Yu Shih, G.V.T. Swapna, Michael Wilson, Margaret Wu, Mark Gerstein, Masayori Inouye, J.F. Hunt, G.T. Montelione

Citations: 130 • 2005

High-throughput crystallography for structural genomics☆

A. Joachimiak

Citations: 114 • 2009

Immobilized metal-affinity chromatography protein-recovery screening is predictive of crystallographic structure success

Ryan Choi, Angela Kelley, D.J. Leibly, Stephen N. Hewitt, Alberto J. Napuli, Wesley Van Voorhis

Citations: 103 • 2011

Facilities and Methods for the High-Throughput Crystal Structural Analysis of Human Proteins

Udo Heinemann, Konrad Büssow, U. Müeller, Patrick Umbach

Citations: 99 • 2003

RIKEN structural genomics beamlines at the SPring-8; high throughput protein crystallography with automated beamline operation

Go Ueno, H. Kanda, Raita Hirose, K. Ida, Takashi Kumasaka, Masaki Yamamoto

Citations: 98 • 2006

A medium-throughput crystallization approach

Gerlind Sulzenbacher, Arnaud Gruez, V. Roig-Zamboni, Silvia Spinelli, C. Alexander Valencia, Fabienne Pagot, Renaud Vincentelli, Christophe Bignon, Aurélia Salomoni, Sacha Grisel, Damien Maurin, Céline Huyghe, Kent Johansson, Alice Grassick, Alain Roussel, Yves Bourne, Sophie Perrier, L. Miallau, Phillippe Cantau, Eric Blanc, Michel Genevois, Alain Grossi, André Zenatti, Valérie Campanacci, Christian Cambillau

Citations: 80 • 2002

A flexible and economical medium-throughput strategy for protein production and crystallization

Nicole J. Moreland, Rachael Ashton, Heather M. Baker, Ivan Ivanović, Sean I. Patterson, Vickery L. Arcus, Edward N. Baker, J. Shaun Lott

Citations: 78 • 2005

Automated technologies and novel techniques to accelerate protein crystallography for structural genomics

Babu A. Manjasetty, A.P. Turnbull, Santosh Panjikar, Konrad Büssow, Mark R. Chance

Citations: 77 • 2008

The Southeast Collaboratory for Structural Genomics:  A High-Throughput Gene to Structure Factory

Michael W. W. Adams, Harry A. Dailey, Lawrence J. DeLucas, Ming Luo, James H. Prestegard, John P. Rose, Bi‐Cheng Wang

Citations: 77 • 2003

Higher-throughput approaches to crystallization and crystal structure determination

Mark J. Fogg, Anthony J. Wilkinson

Citations: 74 • 2008

Beamline Scheduling Software: administration software for automatic operation of the RIKEN structural genomics beamlines at SPring-8

Go Ueno, H. Kanda, Takashi Kumasaka, Masaki Yamamoto

Citations: 68 • 2005

An integrated approach to structural genomics

Udo Heinemann, Juergen Frevert, Klaus‐Peter Hofmann, Gerd Illing, C. T. C. Maurer, Hartmut Oschkinat, Wolfram Saenger

Citations: 59 • 2000

The TB structural genomics consortium crystallization facility: towards automation from protein to electron density

Bernhard Rupp, Brent W. Segelke, Heike I. Krupka, T. Lekin, Johana Schäfer, Adam Zemła, Dominique Toppani, Gyorgy Snell, Thomas Earnest

Citations: 52 • 2002

Structural genomics of the Epstein–Barr virus

Nicolas Tarbouriech, Marlyse Buisson, Thibault Géoui, Susan Daenke, S. Cusack, W.P. Burmeister

Citations: 44 • 2006

An automated small-scale protein expression and purification screening provides beneficial information for protein production

Henry H. Nguyen, Bruno Martínez-Leo, Natalia Oganesyan, Rosalind Kim

Citations: 43 • 2004

Automated mounting, centering and screening of crystals for high-throughput protein crystallography

W. I. Karain, Gleb Bourenkov, Hannes Blume, H.D. Bartunik

Citations: 43 • 2002

Accelerating code to function: sizing up the protein production line

Michele Gilbert, Joanna S. Albala

Citations: 40 • 2002