Yaeta Endo
Papers
7
Total Citations
756
H-Index
7
About
Yaeta Endo is a pioneering biochemist whose research has fundamentally advanced the field of cell-free protein synthesis, with particular expertise in wheat germ-based expression systems. His most influential contribution, a 2002 paper garnering over 523 citations, introduced a eukaryotic cell-free platform capable of high-throughput protein production, offering significant advantages over bacterial and reticulocyte-based systems. This work laid the groundwork for genome-scale proteomics, enabling researchers to synthesize and screen thousands of gene products with unprecedented efficiency. Endo's subsequent studies expanded this technology into full genome-wide protein expression pipelines, refining throughput, yield, and versatility through innovations such as ligation-independent translation vectors and novel purification strategies like the BISOP method, which elegantly removes interfering affinity tags from final protein products. His contributions span structural genomics, functional proteomics, and even autoimmune disease research, where he applied cell-free principles to develop streamlined ELISA systems for detecting rheumatoid factors. Collectively, Endo's body of work has equipped the global research community with powerful, scalable tools for protein production, making him a cornerstone figure in post-genomic science whose methodologies continue to underpin structural biology and drug discovery efforts worldwide.
Research Focus
Key Achievements
Top Papers
- 1A cell-free protein synthesis system for high-throughput proteomics523 citations · 2002
- 2
- 3
- 4
- 5
- 6
- 7