Zhiguo Fan

Hefei University of Technology, Second Military Medical University

Papers

Total Citations

H-Index

About

Zhiguo Fan is a pioneering researcher whose work bridges two seemingly disparate worlds: the remarkable navigational abilities of desert ants and the treatment of metastatic prostate cancer. In his foundational study on desert ant navigation, Fan explored how *Cataglyphis* ants, with limited visual and olfactory cues, can return to their den in a straight line after foraging over distances thousands of times their body length—a seminal paper that has garnered 7 citations and laid groundwork for bio-inspired navigation systems. More recently, Fan has made a significant impact in oncology, leading the NEAR-TOP trial (2025), a multicenter, open-label, randomized controlled study investigating neoadjuvant radiohormonal therapy for oligometastatic prostate cancer. This innovative protocol challenges standard androgen deprivation therapy and chemotherapy, leveraging advances in robotic surgery and precision radiotherapy to potentially overcome treatment resistance. With a citation count already reflecting growing interest, Fan’s work exemplifies translational research—from insect neurobiology to cutting-edge cancer therapeutics—demonstrating a unique ability to draw insights across disciplines. His contributions promise to reshape both our understanding of animal navigation and clinical strategies for prostate cancer.