Toshiaki Hosaka
Papers
1
Total Citations
7
H-Index
1
About
Toshiaki Hosaka is a researcher whose work centers on advancing structural biology through innovative instrumentation, particularly for membrane protein crystallization. His primary research area involves developing practical, high-precision tools to overcome the technical challenges of crystallizing membrane proteins, which are crucial for drug discovery but notoriously difficult to study. Hosaka’s major contribution is the creation of a new manual dispensing system for the *in meso* crystallization method, a technique that uses a lipidic cubic phase to support protein crystal growth. His system, detailed in his most-cited 2014 paper (7 citations), employs a stepping motor-based dispenser with a novel microsyringe to reliably deliver highly viscous lipid mixtures in precise, desired volumes. This design makes the complex *in meso* method more accessible and user-friendly for laboratories lacking expensive robotic setups, thereby lowering the barrier to entry for critical membrane protein research. While his citation count reflects a specialized, early-stage impact, Hosaka’s work represents a notable achievement in practical lab automation, directly enabling more researchers to tackle the challenging crystallization of membrane proteins.
Research Focus
Key Achievements
Top Papers
- 1