About

Pantaleo Romanelli is a pioneering neurosurgeon and radiosurgery specialist whose work has significantly advanced the field of image-guided robotic radiosurgery and the clinical understanding of complex neurological conditions. His research spans two major domains: the management of challenging intracranial and extracranial lesions using CyberKnife radiosurgery, and the characterization of hypothalamic hamartoma-related epilepsy syndromes. Romanelli has made landmark contributions to the treatment of trigeminal neuralgia, optic nerve sheath meningiomas, and spinal lesions, demonstrating that frameless, non-isocentric radiosurgery can achieve excellent outcomes with minimal invasiveness. His single-center series on trigeminal neuralgia — encompassing hundreds of cases — represents some of the largest reported clinical experiences in the field. Equally notable is his work on gelastic seizures and hypothalamic hamartoma, where he helped establish these conditions as a spectrum of potentially reversible but severe epileptic encephalopathies, reshaping clinical understanding and treatment strategies. With a body of work accumulating over 400 citations across neurosurgery, radiosurgery, and epilepsy literature, Romanelli's research consistently bridges technical innovation with meaningful patient outcomes, making him an influential figure for clinicians and trainees navigating the frontiers of functional and radiosurgical neuroscience.

Research Focus

Key Achievements

13
H-Index
22
Papers
534
Total Citations
24
Avg Citations/Paper
🏆 Most Cited Paper
The gelastic seizures-hypothalamic hamartoma syndrome: Facts, hypotheses, and perspectives
68 citations · 2012
📈 Most Prolific Year: 2006 (5 Papers)
🤝 Key Collaborators: 63
🏛 Institutions: Yahoo (United Kingdom), Istituto Neurologico Mediterraneo, University of Messina, Centro Diagnostico Italiano, Stanford University, Ab Medica (Italy)

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
Content generated · 15 days ago